BMIが25未満の女性なら、13年間の中程度（おおよそ１日60分）で2.3kgの体重減少が見込める。2008年に合衆国のガイドラインでは、少くとも１週間当たり150分（7.5 metabolic equivalent [MET] hours per week）の中程度の運動が「健康にはかなりよい」とを推奨している。しかし、身体活動度が、長期的に体重増加を予防するのか不明で、調査された研究。
身体活動と体重増加の予防
Physical Activity and Weight Gain Prevention
JAMA. 2010;303(12):1173-1179.
（メモ）
・1992年から2007年までの平均54.2歳の34,079名の米国人女性を対象にした前向きコホート研究。アウトカムは、体重の変化・
・１週間当たり21MET時間以上の身体活動度群と比較して、7.5から21MET時間未満で0.11 kg (0.04 kg; P = .003)の増加、7.5MET時間未満で0.12 kg (0.04; P = .002)の増加だった。しかし、スタート時にBMIが25未満の場合に維持的に体重は減少（2.3 kg ）し、それ以上のBMIだと逆相関した。
・つまり、BMIが25未満の女性なら、13年間の中程度（おおよそ１日60分）で2.3kgの体重減少が見込める。
Context The amount of physical activity needed to prevent long-term weight gain is unclear. In 2008, federal guidelines recommended at least 150 minutes per week (7.5 metabolic equivalent [MET] hours per week) of moderate-intensity activity for “substantial health benefits.”
Objective To examine the association of different amounts of physical activity with long-term weight changes among women consuming a usual diet.
Design, Setting, and Participants A prospective cohort study involving 34 079 healthy US women (mean age, 54.2 years) from 1992-2007. At baseline and months 36, 72, 96, 120, 144, and 156, women reported their physical activity and body weight. Women were classified as expending less than 7.5, 7.5 to less than 21, and 21 or more MET hours per week of activity at each time. Repeated-measures regression prospectively examined physical activity and weight change over intervals averaging 3 years.
Main Outcome Measure Change in weight.
Results Women gained a mean of 2.6 kg throughout the study. A multivariate analysis comparing women expending 21 or more MET hours per week with those expending from 7.5 to less than 21 MET hours per week showed that the latter group gained a mean (SD) 0.11 kg (0.04 kg; P = .003) over a mean interval of 3 years, and those expending less than 7.5 MET hours per week gained 0.12 kg (0.04; P = .002). There was a significant interaction with body mass index (BMI), such that there was an inverse dose-response relation between activity levels and weight gain among women with a BMI of less than 25 (P for trend < .001) but no relation among women with a BMI from 25 to 29.9 (P for trend = .56) or with a BMI of 30.0 or higher (P for trend = .50). A total of 4540 women (13.3%) with a BMI lower than 25 at study start successfully maintained their weight by gaining less than 2.3 kg throughout. Their mean activity level over the study was 21.5 MET hours per week ( 60 minutes a day of moderate-intensity activity).
Conclusions Among women consuming a usual diet, physical activity was associated with less weight gain only among women whose BMI was lower than 25. Women successful in maintaining normal weight and gaining fewer than 2.3 kg over 13 years averaged approximately 60 minutes a day of moderate-intensity activity throughout the study.
薬物療法の飲めばいい、打てばいいというアクションに比べたら、運動療法、食事療法の方が到底壁は高い。本人が自覚的に継続する必要があり、必要性を感じていても、その結果が10年も、20年も先にわかるものなど誰しも継続できないと思う。どこかに「楽しい」というお遊び要素がプラスされた提案は、どこかにないだろうか？
これから）職場会議、棚卸し、ああ、年度末〆。
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